Arachidonic Acid

HB-5506-FG
Product Product Code Pack Size Concentration RT Storage 2-8°C Storage Shelf Life
Arachidonic Acid HB-5506-FG 2 x 1.0 ml 5mg/ml 8 hours 14 days 3 years

 

Hart Biologicals Arachidonic Acid Reagent is used to diagnose platelet dysfunction, or normal platelet activity in human platelet rich plasma or whole blood. Arachidonic Acid is a fatty acid present in the granules and membranes of human platelets. It is liberated from phospholipids and, in the presence of the enzyme cyclo-oxygenase 1 (COX-1), incorporates oxygen to form the endoperoxide prostaglandin G2 (PGG2). PGG2 is then quickly transformed to prostaglandin H2 (PGH2) which in turn is converted to thromboxane A2 a potent inducer of platelet aggregation.

In vitro addition of Arachidonic Acid to normal platelet rich plasma results in a burst of oxygen consumption, thromboxane formation and platelet aggregation.

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Product Product Code Pack Size Concentration RT Storage 2-8°C Storage Shelf Life
Arachidonic Acid HB-5506-FG 2 x 1.0 ml 5mg/ml 8 hours 14 days 3 years

 

Hart Biologicals Arachidonic Acid Reagent is used to diagnose platelet dysfunction, or normal platelet activity in human platelet rich plasma or whole blood. Arachidonic Acid is a fatty acid present in the granules and membranes of human platelets. It is liberated from phospholipids and, in the presence of the enzyme cyclo-oxygenase 1 (COX-1), incorporates oxygen to form the endoperoxide prostaglandin G2 (PGG2). PGG2 is then quickly transformed to prostaglandin H2 (PGH2) which in turn is converted to thromboxane A2 a potent inducer of platelet aggregation.

In vitro addition of Arachidonic Acid to normal platelet rich plasma results in a burst of oxygen consumption, thromboxane formation and platelet aggregation.